For years, Salesforce has been the dominant tool for sales teams, serving as the central system for tracking deals and customer data. Now, New York-based startup Actively AI is betting its AI agents can do much of that work autonomously — and it’s coming for Salesforce’s crown. https://www.forbes.com/sites/sofiachierchio/2026/04/28/meet-the-250-million-startup-challenging-salesforce-with-ai-agents/

Salesforce today announced that Moderna has selected Salesforce’s Agentforce Life Sciences for Customer Engagement to unify the biotechnology company’s global commercial operations. The collaboration supports Moderna’s vision to enable a single, connected platform to engage customers, streamline field and customer service operations, and deliver the best customer experience based on a 360-degree understanding of their customers. https://firstwordpharma.com/story/7232403

Salesforce CEO Marc Benioff is breaking ranks with the prevailing tech-industry message on artificial intelligence (AI) and jobs. In a Fortune interview published April 27, 2026, Benioff pushed back on the idea that AI will wipe out entry-level white-collar work and said Salesforce will hire 1,000 new graduates to back it up. https://247wallst.com/investing/2026/04/28/salesforce-ceo-marc-benioff-says-ai-wont-kill-entry-level-jobs-and-hes-hiring-1000-new-grads-to-prove-it/

Employers invite legal risk when they make termination decisions involving employees who are caregivers for people with disabilities or who either have taken or are in the process of taking protected medical leave. https://www.hrdive.com/news/salesforce-negative-record-employee-fmla-leave/818598/

Alcon, the eye-care company operating in more than 60 countries, built over 900 AI agents in under a year. “Everyone went and built their own agents — business users and IT users alike,” said Sreenivasa Patibandla, the company’s Director of System Integrations and APIs. It’s a useful opening to Salesforce’s 2026 Connectivity Benchmark Report, because it illustrates how agent deployment has moved faster than the frameworks designed to govern it. https://www.uctoday.com/product

What happens if you build technology that has the potential to eat the lunch of your loyal community? Of the advocates, solution architects, and developers that have spent a decade of their collective blood, sweat and tears driving a big part of your success? It looks like Salesforce is going to have to figure that out — before most people have even seen the problem coming. Because as I discovered at its recent TDX conference, when one of enterprise software’s most ambitious